S100B single nucleotide polymorphisms exhibit sex-specific associations with chronic pain in sickle cell disease in a largely African-American cohort.

Ellie H JhunNilanjana SadhuYing HeYingwei YaoDiana J Wilkie Robert E Molokie Zaijie Jim Wang

Published in: PloS one (2020)

S100B SNPs and haplotypes are associated with chronic pain in female, but not male, patients with SCD, implicating a potential role of S100B polymorphism in SCD pain heterogeneity in a sex-dependent manner.

Keyphrases

chronic pain
african american
sickle cell disease
pain management
genome wide
single cell
human health
gene expression
spinal cord
climate change
neuropathic pain