Pharmacological characterization of the antidiabetic drug metformin in atherosclerosis inhibition: A comprehensive insight.

Areej TurkistaniHaydar M Al-KuraishyAli I Al-GareebAthanasios AlexiouMarios PapadakisMostafa M BahaaSalah Al-WindyGaber El-Saber Batiha

Published in: Immunity, inflammation and disease (2024)

In conclusion, metformin is an effective therapeutic strategy against the development and progression of AS, mainly through activation of the KLF2/Nrf2 axis.

Keyphrases

oxidative stress
cardiovascular disease
transcription factor
type diabetes
emergency department
drug induced
electronic health record