Multi-omics profiling of primary hepatic stellate cells from advanced liver fibrosis patients reveals distinctive molecular signatures.

Yutong DongYuwei LiuXu LiuHeming MaYahui LiuGuoyue Lv Junqi Niu

Published in: Journal of gastroenterology and hepatology (2023)

Our results revealed the major transcriptomic and proteomic changes during liver cirrhosis process and identified new biomarkers and potential therapeutic targets for advanced liver fibrosis.

Keyphrases

liver fibrosis
single cell
end stage renal disease
newly diagnosed
chronic kidney disease
prognostic factors
genome wide