MicroRNA Signatures for circulating CD133-positive cells in hepatocellular carcinoma with HCV infection.

Abdel Rahman N ZekriEnas Reda El-SisiAmira Salah El-Din YoussefMahmoud M KamelAuhood NassarOla Sayed AhmedMohamed El KassasAhmed Barakat BarakatAlaa Ismail Abd El-MotalebAbeer A Bahnassy

Published in: PloS one (2018)

We identified a miRNA panel comprised of four miRNAs (miR-192, miR-122, miR-181b and miR-125a-5p) that may serve as a molecular tool for characterization of the CD133+ cells associated with different stages of hepatocarinogensis. This panel may aid in developing a new target therapy specific for those CD133+ cells.

Keyphrases

induced apoptosis
cell cycle arrest
cell proliferation
long non coding rna
endoplasmic reticulum stress
oxidative stress
human immunodeficiency virus
single molecule