Could HE4 level measurements during first-line chemotherapy predict response to treatment among ovarian cancer patients?
Anita Chudecka-GłazAneta Cymbaluk-PłoskaMałgorzata WężowskaJanusz MenkiszakPublished in: PloS one (2018)
The significant effect of the normalization of the HE4 marker after therapy and 50% reduction of HE4 levels before interval cytoreductive surgery on PFS and OS confirmed that HE4 might be an independent prognostic factor of treatment response. HE4 measurements performed during first-line treatment of ovarian cancer may have prognostic significance.