Value of Serum miRNA-96-5p and miRNA-99a-5p as Diagnostic Biomarkers for Hepatocellular Carcinoma.
Amal F GharibEmad M EedAmany S KhalifaNermin RaafatSomaia Shehab-EldeenHany R AlwakeelEhab DarwieshAbdallah EssaPublished in: International journal of general medicine (2022)
Using miRNA-96-5p and miRNA-99a-5p in combination with AFP increased both sensitivity and specificity for the diagnosis of HCC. Furthermore, serum levels were linked to tumor size and metastasis. These findings suggested that serum miRNA-96-5p and miRNA-99a-5p could be used as non-invasive biomarkers for the diagnosis of HCC.
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