Overall vertical transmission of HCV, transmission net of clearance, and timing of transmission.
Anthony E AdesFabiana GordonKaren ScottIntira J CollinsClaire ThorneLucy PembreyElizabeth ChappellEugènia Mariné-BarjoanKarina ButlerGiuseppe IndolfiDiana M GibbAli JuddPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)
Overall VT rates are about 24% higher than previously assumed, but the risk of infection persisting beyond age 5 years is about 38% lower. The results can inform design of trials of to prevent or treat pediatric HCV infection, and strategies to manage children exposed in utero.
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