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Multi-omics and experimental analysis unveil theragnostic value and immunological roles of inner membrane mitochondrial protein (IMMT) in breast cancer.

Hung-Yu LinHsing-Ju WuPei-Yi Chu
Published in: Journal of translational medicine (2023)
This study combined a multi-omics survey with experimental verification to reveal the novel clinical significance of IMMT in BC, demonstrating its role in TIME, cancer cell growth and mitochondrial fitness, and identified pyridostatin as a promising drug candidate for the development of precision medicine.
Keyphrases
  • single cell
  • oxidative stress
  • papillary thyroid
  • physical activity
  • body composition
  • genome wide
  • squamous cell
  • emergency department
  • gene expression
  • amino acid
  • childhood cancer
  • young adults
  • drug induced
  • small molecule