Novel age-associated DNA methylation changes and epigenetic age acceleration in middle-aged African Americans and whites.
Salman M TajuddinDena G HernandezBrian H ChenNicole Noren HootenNicolle A ModeMike A NallsAndrew B SingletonNgozi EjioguKumaraswamy Naidu ChitralaAlan B ZondermanMichele Kim EvansPublished in: Clinical epigenetics (2019)
AAs have more wide-spread methylation changes than whites. Race and sex interact to underlie biological age acceleration suggesting altered DNA methylation patterns may be important in age-associated health disparities.