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Validation of genetic markers associated with survival in colorectal cancer patients treated with oxaliplatin-based chemotherapy.

Hanla A ParkPetra SeiboldDominic EdelmannAxel BennerFrederico CanzianElizabeth AlwersLina JansenMartin SchneiderMichael HoffmeisterHermann BrennerJenny Chang-Claude
Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2021)
We did not robustly confirm previously reported SNPs despite some suggestive findings but identified further potential predictive SNPs, which warrant further investigation in well-powered studies.
Keyphrases
  • genome wide
  • dna methylation
  • copy number
  • genome wide association
  • locally advanced
  • case control
  • free survival
  • human health
  • gene expression
  • squamous cell carcinoma
  • radiation therapy
  • risk assessment