Lymphovascular invasion quantification could improve risk prediction of lymph node metastases in patients with submucosal (T1b) esophageal adenocarcinoma.
Steffi Elisabeth Maria van de VenLucia SuzukiAnnieke Willemien GotinkFiebo J C Ten KateDaan NieboerBas L A M WeustenLodewijk A A BrosensRichard van HillegersbergLorenza Alvarez HerreroCees A SeldenrijkAlaa AlkhalafFreek C P MollWouter CurversIneke G van LijnschotenThjon J TangHans van der ValkWouter B NagengastGursah Kats-UgurluJohn T M PlukkerMartin H M G HoubenJaap S van der LaanRoos E PouwJacques J G H M BergmanSybren L MeijerMark I van Berge HenegouwenBas P L WijnhovenPieter J F de JongeMichael DoukasMarco J BrunoKatharina BiermannArjun D KochPublished in: United European gastroenterology journal (2021)
The risk of metastases is higher when more LVI foci are present. Quantification of LVI could be useful for a more precise risk estimation of metastases. This model needs to be externally validated before implementation into clinical practice.