Safety and Efficacy of Alendronate to Treat Osteopenia in Children During Therapy for Acute Lymphoblastic Leukemia: A Retrospective Cohort Study of Sequential Outcomes.

Paula MacDonaldAmy CranstonMisha VirdeeTroy FarncombeUma AthaleRonald D Barr

Published in: Journal of pediatric hematology/oncology (2022)

Alendronate appears to be well tolerated and moderately effective in osteopenic children with ALL. Whether it offers protection against relapse of leukemia needs further study.

Keyphrases

acute lymphoblastic leukemia
young adults
bone marrow
type diabetes
allogeneic hematopoietic stem cell transplantation
adipose tissue
weight loss
glycemic control