HIV-seroconversion among HIV-1 serodiscordant married couples in Tanzania: a cohort study.
Soledad ColombeJames BeardBaltazar MtengaPeter LutonjaJulius MngaraClaudia J de DoodGovert J van DamPaul L A M CorstjensSamuel KalluvyaMark UrassaJim ToddJennifer A DownsPublished in: BMC infectious diseases (2019)
Our study suggests that rates of HIV-1 seroconversion of sero-discordant partners are much higher within marriage than in the general population in Tanzania. The major risk factor for HIV-1 seroconversion is sex of the serodiscordant spouse, with female spouses being at very high risk of acquiring HIV infection. This suggests that future programs that target serodiscordant couples could be a novel and effective means of preventing HIV-1 transmission in Tanzania.