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Novel Cellulose Fibre-Based Flexible Plasmonic Membrane for Point-of-Care SERS Biomarker Detection in Chronic Wound Healing.

Jayakumar PerumalHann Qian LimAmalina Binte Ebrahim AttiaRiazul RaziqDavid Ian LeavesleyZee UptonU S DinishMalini Olivo
Published in: International journal of nanomedicine (2021)
Our SERS sensing platform achieved detection limits in the µM to sub-nM range and displayed high sensitivity and selectivity. This could result in a cheap, point-of-care device that provides a non-invasive measure of cutaneous wound healing in real time. We envision that these flexible substrates after activation may be incorporated into wound dressings in future for routine monitoring of wound healing status.
Keyphrases
  • wound healing
  • label free
  • gold nanoparticles
  • sensitive detection
  • loop mediated isothermal amplification
  • real time pcr
  • raman spectroscopy
  • high throughput
  • ionic liquid
  • clinical practice
  • structural basis