Functional analysis reveals ionotropic GABA receptor subunit RDL is a target site of ivermectin and fluralaner in the yellow fever mosquito, Aedes aegypti.

Qiuhui WangHaocheng WangYingxin ZhangJing ChenArchana UpadhyayBiswajit BhowmickJiayu HangShaoying WuChenghong LiaoQian Han

Published in: Pest management science (2022)

Our study revealed that Ae-RDL subunit is a target of ivermectin and fluralaner, providing new insights into the insecticidal mechanism of both compounds in Ae. aegypti. © 2022 Society of Chemical Industry.

Keyphrases

aedes aegypti
zika virus
dengue virus
protein kinase
single cell
drug administration