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LSD1-directed therapy affects glioblastoma tumorigenicity by deregulating the protective ATF4-dependent integrated stress response.

Stefania FalettiDaniela OstiElena CeccacciCristina RichichiBrunella CostanzaLuciano NicosiaRoberta NoberiniGiulia MarottaLaura FuriaMario R FarettaSilvia BrambillascaMicaela QuartoLuca BerteroRenzo L BoldoriniBianca PolloSara GandiniDavide CoraSaverio MinucciCiro MercurioMario VarasiTiziana BonaldiGiuliana Pelicci
Published in: Science translational medicine (2021)
[Figure: see text].
Keyphrases
  • transcription factor
  • endoplasmic reticulum stress
  • stem cells
  • bone marrow
  • mesenchymal stem cells