30 Gy in 4 Stereotactic Body Radiotherapy Fractions for Complex Spinal Metastases: Mature Outcomes Supporting This Novel Regimen.

Daniel Moore Freitas PalharesArjun SahgalK Liang ZengSten MyrehaugChia-Lin TsengJay DetskyHanbo ChenMark RuschinEshetu G AtenafuJeff WilsonJeremie LaroucheLeodante da CostaPejman Jabehdar MaralaniHany Soliman

Published in: Neurosurgery (2023)

30 Gy in 4 fractions was safe and efficacious despite the population being at increased risk of toxicity. The lower risk of VCF in previously stabilized segments highlights the potential for a multimodal treatment approach for complex metastases, especially for those with a CTV volume of ≥72 cc.

Keyphrases

early stage
spinal cord
radiation therapy
locally advanced
pain management
radiation induced
type diabetes
climate change
risk assessment
insulin resistance
rectal cancer