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Too Sensitive or Just Right?

Dana MartinSteven Christopher SmithAlden ChesneyColleen Jackson-CookRaghavendra Pillappa
Published in: American journal of clinical pathology (2022)
Overall, D5F3 showed greater stain intensity and proportion staining than ALK1 in ALK-positive ALCL cases, which is especially helpful in limited samples. Caution and consideration of orthogonal ALK testing types is recommended, especially for cases with weak or focal staining.
Keyphrases
  • advanced non small cell lung cancer
  • flow cytometry
  • high intensity
  • epidermal growth factor receptor