Definitive Intensity-Modulated Chemoradiation for Anal Squamous Cell Carcinoma: Outcomes and Toxicity of 428 Patients Treated at a Single Institution.
Emma B HollidayVan K MorrisBenny JohnsonCathy EngEthan Bernard LudmirPrajnan DasBruce D MinskyCullen TaniguchiGrace L SmithEugene J KoayAlbert C KoongMarc E DelclosJohn M SkibberMiguel A Rodriguez-BigasY Nancy YouBrian K BednarskiMathew M TillmanGeorge J ChangKristofer JenningsCraig A MessickPublished in: The oncologist (2022)
Our results suggest IMRT-based CRT with concurrent fluoropyrimidine and cisplatin is a safe and feasible option for patient with SCCA and may cause less acute toxicity. The role for radiation dose escalation is unclear and requires further study.