Successful use of a therapeutic trial of graduated volume and dose escalation for postoperative head and neck radiotherapy in a Fanconi anemia patient.

Luke M LewisAlice L TangTrisha M Wise-DraperKasiani C MyersJoel S GreenbergerVinita Takiar

Published in: Head & neck (2020)

The FA patient population has a clear need for adjuvant treatment regimens given their predilection for HNSCC. A therapeutic trial may allow FA and other radiosensitive patients to trial radiation with the option to terminate treatment before any severe side effects occur and for some to complete a full course of treatment.

Keyphrases

clinical trial
study protocol
early stage
end stage renal disease
chronic kidney disease
phase iii
patients undergoing
squamous cell carcinoma
early onset
peritoneal dialysis
patient reported outcomes