Immunosuppression by a subconjunctival implant releasing dexamethasone in a rabbit model of penetrating keratoplasty.

Emmanuel CrouzetThibaud GarcinAnne-Sophie GauthierZhiguo HeChantal PerracheXavier DelavenneThierry BassetMichel Peoc'hPhilippe GainGilles Thuret

Published in: The British journal of ophthalmology (2018)

In this PK model characterised by a high rejection rate, a subconjunctival dexamethasone implant was for 6 weeks as effective as the topical form in preventing allograft rejection.

Keyphrases

high dose
low dose
soft tissue
gestational age
preterm birth