No Association Between ADIPOQ or MTHFR Polymorphisms and Gestational Diabetes Mellitus in South African Women.

Stephanie Dias Sumaiya AdamPaul RheederCarmen Pheiffer

Published in: Diabetes, metabolic syndrome and obesity : targets and therapy (2021)

ADIPOQ rs266729 and rs17300539 and MTHFR rs1801133 polymorphisms are not associated with GDM in a population of black South African women. These findings suggest that these single nucleotide polymorphisms (SNPs) do not individually increase GDM risk in the African population. However, the role of these SNPs in possible gene-gene or gene-environment interactions remain to be established.

Keyphrases

genome wide
copy number
pregnancy outcomes
polycystic ovary syndrome
genome wide identification
dna methylation
pregnant women
gene expression
type diabetes
adipose tissue
cervical cancer screening
insulin resistance
genome wide analysis