Circulating plasma exosomes in obstructive sleep apnoea and reverse dipping blood pressure.

Abdelnaby Khalyfa David GozalWen-Ching ChanJorge AndradeBharati Prasad

Published in: The European respiratory journal (2020)

Patients with RDBP have altered miRNA cargoes in circulating exosomes that invoke in vitro endothelial dysfunction. A selected number of circulating exosomal miRNAs play an important role in abnormal circadian regulation of blood pressure and may provide prognostic biomarkers of CVD risk in OSA.

Keyphrases

blood pressure
mesenchymal stem cells
stem cells
hypertensive patients
heart rate
obstructive sleep apnea
positive airway pressure
physical activity
type diabetes
blood glucose
sleep quality
adipose tissue
bone marrow
skeletal muscle
weight loss