Warts and all: Fingolimod and unusual HPV-associated lesions.
James Douglas TriplettAllan G KermodeAlastair CorbettStephen W ReddelPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2018)
Cutaneous warts are associated with human papilloma virus (HPV) infection, suggesting an increased risk of other HPV-driven conditions such as cervical cancer following fingolimod administration. HPV viruses are responsible for approximately 90% of cervical cancers as well as a significant portion of anogenital cancers and have a high prevalence in sexually active adults. Given the reduced immune response to viral infections and potential impaired cancer surveillance in those receiving fingolimod, HPV vaccination and frequent assessment for the development of HPV-associated malignancies are recommended.