Effects on QT interval of hydroxychloroquine associated with ritonavir/darunavir or azithromycin in patients with SARS-CoV-2 infection.

Luigi MoschiniMarco LoffiValentina RegazzoniGiuseppe Di TanoElisa GherbesiGian Battista Danzi

Published in: Heart and vessels (2020)

Hydroxychloroquine with both ritonavir/darunavir or azithromycin therapy significantly increased the QTc-interval at 7 days. The risk of developing malignant arrhythmias remained relatively low when these drugs were administered for a limited period of time.

Keyphrases

hiv infected patients
antiretroviral therapy
drug induced
congenital heart disease
respiratory syndrome coronavirus