Functional and cell surface characteristics of periodontal ligament cells (PDLCs) on RGD-synthetic polypeptide conjugate coatings.

Zambaga KhorolsurenOrsolya LangEva PallingerAnna FoldesGyulai-Gaál SzabolcsGabor VargaGabor MezoJanos Vag László Kőhidai

Published in: Journal of periodontal research (2020)

Our study demonstrates that SAK-c[RGDfC] and AK-c[RGDfC] improved adhesion and migration of PDLCs and supported osteogenic differentiation of PDLCs. These cyclic RGD peptides proved to be applicable biocompatible material in regenerative medicine.

Keyphrases

cell surface
induced apoptosis
cell cycle arrest
oxidative stress
biofilm formation
endoplasmic reticulum stress