Discrepancy Between Genetically Predicted and Observed BMI Predicts Incident Type 2 Diabetes.

Tae-Min RheeJaewon Choi Hyunsuk LeeJordi MerinoJun-Bean ParkSoo Heon Kwak

Published in: Diabetes care (2024)

Having a higher BMI than genetically predicted is associated with an increased risk of T2D. These findings underscore the potential to reassess T2D risk based on individual levels of obesity using genetic thresholds for BMI.

Keyphrases

type diabetes
weight gain
body mass index
insulin resistance
cardiovascular disease
metabolic syndrome
weight loss
glycemic control
high fat diet induced
adipose tissue
physical activity
risk assessment
human health
skeletal muscle
climate change