MicroRNA-26b-5p Targets DAPK1 to Reduce Intestinal Ischemia/Reperfusion Injury via Inhibition of Intestinal Mucosal Cell Apoptosis.

Bowei ZhouWenjuan ZhangZhengzheng YanBingcheng ZhaoJin ZhaoWeijie FengXiaodong ChenCai LiWei-Feng Liu

Published in: Digestive diseases and sciences (2021)

Our findings show that miR-26b-5p may prevent intestinal I/R injury via targeting DAPK1 and inhibiting intestinal mucosal cell apoptosis, suggesting that this miRNA may be a viable target for the treatment of intestinal I/R injury.

Keyphrases

ischemia reperfusion injury
cell proliferation
signaling pathway
oxidative stress
cancer therapy
ulcerative colitis
replacement therapy
smoking cessation