Kevin Lafferty and the lymphocyte costimulator: theory and practice in Canberra.

Published in: Immunology and cell biology (2023)

Between 1969 and 1983 the lab of Kevin Lafferty in Canberra developed the concept of the T-cell "costimulator," an essential second signal for activation. A great deal of the work appeared in this journal before it was known as Immunology & Cell Biology (ICB). As part of the 100-year anniversary of the journal, I offer a personal reflection on Kevin's legacy and impact.

Keyphrases

single cell
primary care
healthcare
cell therapy
quality improvement
stem cells
mesenchymal stem cells
bone marrow