Characteristics of Patients With Initial Clostridioides difficile Infection (CDI) That Are Associated With Increased Risk of Multiple CDI Recurrences.
Alice Y GuhRongxia LiLauren KorhonenLisa G WinstonErin ParkerChristopher A CzajaHelen JohnstonElizabeth BasiliereJames MeekDanyel OlsonScott K FridkinLucy E WilsonRebecca PerlmutterStacy M HolzbauerPaige D'HeillyErin C PhippsKristina G FloresGhinwa K DumyatiRebecca PierceValerie L S OcampoChristopher D WilsonJasmine J WatkinsDale N GerdingL Clifford McDonaldPublished in: Open forum infectious diseases (2024)
Patients with iCDI who are older, on hemodialysis, or had recent hospitalization or nitrofurantoin use had increased risk of mrCDI and may benefit from early use of adjunctive therapy to prevent mrCDI. If confirmed, these findings could aid in clinical decision making and interventional study designs.