Determining the Risk of Elevated Digoxin Concentrations Following Loading Dose in Patients With Acute and Chronic Kidney Disease.
Mikaela R YoungStephen H RappaportSarah BelzDavid C KaufmanCurtis E HaasPublished in: The Annals of pharmacotherapy (2023)
This is the first study in routine clinical practice evaluating the relationship between kidney function and digoxin peak concentrations that differentiates AKI from CKD. We did not find a relationship between kidney function and peak concentrations; however, the group with CKD was underpowered.