Disability in multiple sclerosis is related to thalamic connectivity and cortical network atrophy.
Menno Michiel SchoonheimDaniela PinterStefanos E ProuskasTommy Aa BroedersLukas PirpamerMicheal KhalilStefan RopeleBernard Mj UitdehaagFrederik BarkhofChristian EnzingerJeroen Jg GeurtsPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2021)
The severity of disability in MS was related to increased static thalamic FC with the SMN. Thalamic FC changes were only related to cortical network atrophy, but not to thalamic atrophy.