Reduced Tolerogenic Program Death-Ligand 1-Expressing Conventional Type 1 Dendritic Cells Are Associated with Rapid Decline in Chronic Obstructive Pulmonary Disease.

Kuan-Yuan ChenWei-Lun Sun Sheng-Ming WuPo-Hao FengChiou-Feng LinTzu-Tao ChenYueh-Hsun LuShu-Chuan HoYueh-Hsi ChenKang-Yun Lee

Published in: Cells (2024)

cDC1 was reduced in the patients with COPD, and the tolerogenic role was suppressed with susceptibility to self-antigens and linked to rapid decline caused by Th17-skewed chronic inflammation.

Keyphrases

dendritic cells
regulatory t cells
immune response
loop mediated isothermal amplification
chronic obstructive pulmonary disease
oxidative stress
quality improvement
lung function
cell cycle