Genetic polymorphisms linked to extreme postorthodontic external apical root resorption in Koreans.

Jing LiuKwanwoo ParkYoon Jeong ChoiJi Hyun LeeJung Yul Cha

Published in: Progress in orthodontics (2024)

Extreme phenotype analysis has identified eleven SNPs related to genes TNFSF11, TNFRSF11B, WNT3A, SFRP2, LRP6, P2RX7, and LRP1 that are associated with severe root resorption in the Korean population. These findings will contribute to the development of predictive diagnostic tools for identifying severe root resorption that may occur during orthodontic treatment.

Keyphrases

genome wide
climate change
early onset
bone loss
stem cells
cell proliferation
gene expression
data analysis