Autophagy modulation alleviates cryoinjury in murine spermatogonial stem cell cryopreservation.

Sang-Eun JungJin Seop AhnYong-Hee KimHui-Jo OhBang-Jin KimSun-Uk KimBuom-Yong Ryu

Published in: Andrology (2021)

A basal level of autophagy plays a critical role in the pro-survival response of frozen SSCs after thawing; herein, a new approach by which SSC cryoprotective efficiency can be improved was identified.

Keyphrases

stem cells
cell death
endoplasmic reticulum stress
signaling pathway
oxidative stress
mouse model
anti inflammatory