Subtypes of high-grade breast ductal carcinoma in situ (DCIS): incidence and potential clinical impact.

Hossein SchandizDaehoon ParkYan Liu KaiserMarianne LyngraInger Solvang TalleraasJürgen GeislerTorill Sauer

Published in: Breast cancer research and treatment (2023)

High-grade DCIS exhibits all the molecular subtypes previously identified in IBC, but with a somewhat different distribution in our cohort. HER2-enriched subtype is substantially related to the presence of an invasive component in DCIS; consequently, it is regarded as a high-risk entity.

Keyphrases

high grade
low grade
risk factors
single molecule
climate change