Obesity in HFpEF with and without diabetes - Risk factor or innocent bystander?

Suriya PrausmüllerAnnika WeidenhammerGregor HeitzingerGeorg SpinkaGeorg GoliaschHenrike ArfstenRamy Abdel MawgoudCornelia GablerGuido StrunkChristian HengstenbergMartin HülsmannPhilipp E Bartko Noemi Pavo

Published in: European journal of preventive cardiology (2023)

Among the various phenotypes of HFpEF, the T2DM phenotype is specifically associated with greater disease burden. Higher BMI is linked to improved survival in HFpEF overall, while this effect neutralises in patients with concomitant T2DM. Advising BMI-based weight targets and weight loss may be pursued with different intensity in the management of HFpEF, particularly in the presence of T2DM.

Keyphrases

weight loss
glycemic control
weight gain
body mass index
bariatric surgery
type diabetes
roux en y gastric bypass
risk factors
gastric bypass
metabolic syndrome
cardiovascular disease
insulin resistance
physical activity
high intensity
body weight