Human leukocyte antigen-B27 typing by flow cytometry: Comparison of three CE-IVD methods.

Louis WaeckelAnne KennelAnne-Emmanuelle BergerClaude Lambert

Published in: Cytometry. Part B, Clinical cytometry (2022)

The three flow cytometry kits displayed satisfying performances but need adjustments. The DuraClone B27™ kit seems to be the best while the IOTest™ kit is not conclusive in 8% of cases. In most cases the use of molecular biology can be spared, but genotyping remains essential for patients whose HLA-B27 status cannot be determined with confidence by flow cytometry.

Keyphrases

flow cytometry
end stage renal disease
ejection fraction
newly diagnosed
endothelial cells
chronic kidney disease
prognostic factors
genome wide
high throughput
peritoneal dialysis
gene expression
peripheral blood
spinal cord
clinical evaluation