Adipose-derived mesenchymal stem cells cultured in serum-free medium attenuate acute contrast-induced nephropathy by exerting anti-apoptotic effects.

Mitsuki KadonoAyumu NakashimaNaoki IshiuchiKensuke SasakiYoshie MiuraSatoshi MaedaAsuka FujitaAyano SasakiShogo NagamatsuTakao Masaki

Published in: Stem cell research & therapy (2023)

These findings strongly suggest that SF-MSCs improve CIN in model mice by exerting anti-apoptotic effects in a paracrine manner. Thus, SF-MSCs represent a potential novel therapy for CIN.

Keyphrases

mesenchymal stem cells
umbilical cord
cell death
drug induced
magnetic resonance
liver failure
endothelial cells
high glucose
anti inflammatory
computed tomography
metabolic syndrome
adipose tissue
wild type
mechanical ventilation