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Evaluation of a modified quantitative polymerase chain reaction assay for genus Schistosoma detection using stool and urine samples from schistosomiasis endemic areas in Kenya.

Henry M KanyiRichelle W KihoroBenard ChiengSylvie ArakaHenry EmisikoThierry RamosSarah NogaroSammy M Njenga
Published in: PloS one (2024)
This study documents a single day-one sample modified Schistosoma qPCR assay as a powerful improved molecular assay for the detection of schistosomiasis infection that utilize either stool or urine samples. The assay is therefore recommended for monitoring in areas with low infection levels to enable accurate determination of the disease's control endpoint.
Keyphrases
  • high throughput
  • high resolution
  • loop mediated isothermal amplification
  • label free
  • single cell
  • molecularly imprinted
  • quantum dots