Utility and cost evaluation of multiparametric magnetic resonance imaging for the assessment of non-alcoholic fatty liver disease.
Peter J EddowesN McDonaldN DaviesS I K SempleT J KendallJ HodsonPhilip Noel NewsomeR B FlinthamR WesolowskiL BlakeR V DuarteC J KellyA H HerlihyM D KellyS P OlliffS G HübscherJonathan Andrew FallowfieldGideon M HirschfieldPublished in: Alimentary pharmacology & therapeutics (2017)
Multiparametric MRI accurately identified patients with steatosis, stratifies those with NASH or simple steatosis and reliably excludes clinically significant liver disease with superior negative predictive value (83.3%) to liver stiffness (42.9%) and ELF (57.1%). For the risk stratification of NAFLD, multiparametric MRI was cost effective and, combined with transient elastography, had the lowest cost per correct diagnosis.