A meta-analysis of the influence of ADRB2 genetic polymorphisms on albuterol (salbutamol) therapy in patients with asthma.

Keiko HikinoShinobu KobayashiErika OtaTaisei MushirodaKevin Y UrayamaTohru Kobayashi

Published in: British journal of clinical pharmacology (2020)

Synthesis of the studies to date shows weak evidence for an association between ADRB2 Arg16Gly and Gln27Glu and FEV1.0% after albuterol use, results of which underscore significant heterogeneity across studies and the need for careful design and sample size considerations.

Keyphrases

case control
chronic obstructive pulmonary disease
lung function
single cell
stem cells
cystic fibrosis
bone marrow
allergic rhinitis
cell therapy
air pollution
replacement therapy