Structural identification of an polysaccharide isolated from Epimedium brevicornum and its beneficial effect on promoting osteogenesis in osteoblasts induced by high glucose.

Shan Shan LeiBo LiXiao Wen HuangXu Pin WangShan XiongRui DuanLin Zi Li

Published in: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (2023)

These results indicate that EBPC1 treatment can promote osteogenesis during DOP, which can ameliorate apoptosis by regulating Bax/Bcl2 and accelerating osteogenesis in osteoblasts.

Keyphrases

high glucose
endothelial cells
bone regeneration
oxidative stress
endoplasmic reticulum stress
cell death
induced apoptosis
cell cycle arrest
signaling pathway
bioinformatics analysis
pi k akt