Reappraisal of the Medical Research Council Antiepileptic Drug Withdrawal Study: Contamination-adjusted and dose-response re-analysis.

Samuel W TermanChang WangLu WangKees P J BraunWillem M OtteGeertruida SlingerWesley T KerrMorten I LossiusLaura BonnettJames F BurkeAnthony G Marson

Published in: Epilepsia (2022)

CA ITT results (the effect of actually withdrawing ASMs on seizures) were slightly greater than ITT effects (the effect of recommend withdrawing ASMs on seizures). How these findings affect clinical practice must be individualized.

Keyphrases

clinical practice
emergency department
health risk
drug induced