Prognostic model to predict the incidence of radiographic knee osteoarthritis.

Rocío Paz-GonzálezVanesa Balboa-BarreiroLucia LouridoValentina CalamiaPatricia Fernandez-PuenteNatividad OreiroCristina Ruiz-Romero Francisco Javier Blanco

Published in: Annals of the rheumatic diseases (2024)

A novel prognostic model based on common clinical variables and protein biomarkers was developed and externally validated to predict rKOA incidence over a 96-month period in individuals without any radiographic signs of disease. The resulting nomogram is a useful tool for stratifying high-risk populations and could potentially lead to personalised medicine strategies for treating OA.

Keyphrases

knee osteoarthritis
risk factors
lymph node metastasis
binding protein
genetic diversity