Mononuclear cells from patients with rhupus are influenced by TNF in their production of gp130/sIL-6Rb and APRIL.
Luis M Amezcua-GuerraFausto Sánchez-MuñozSantiago Guzmán-GarcíaRicardo Márquez-VelascoEnrique Becerril-VillanuevaYadira Vázquez-PanchosYaneli Juárez-VicuñaPublished in: Lupus science & medicine (2023)
These findings suggest that the spontaneous production of molecules by cells from patients with rhupus may contribute to the development of the disease, and that TNF may play a role in this process by regulating the secretion of gp130/sIL-6Rb and APRIL.
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