Neurological and vestibular findings in three cases of Multiple Sclerosis.
Alanna Stefany de Lima EvangelistaJose Diniz JuniorAna Paula Machado CostaMário Emílio Teixeira Dourado JuniorErika Barioni MantelloPublished in: CoDAS (2023)
Multiple sclerosis (MS) is a chronic and inflammatory autoimmune disease that affects the central nervous system (CNS). Dysfunction of body balance is also a common symptom and may be related to neurological injuries resulting from this disease. The aim of this study was to characterize the neurological and vestibular findings of three clinical cases diagnosed with MS. Data on the neurological evaluation and the magnetic resonance imaging of the skull were collected from the medical records. The patients responded to an initial interview and underwent clinical assessment of body balance and Video Head Impulse Test (vHIT). Vestibular symptoms and alterations were observed in at least one of the clinical tests of body balance and cerebellar function. In vHIT, changes were obtained in oculomotor tests, such as the presence of semi-spontaneous nystagmus and in parameters of the saccade test, and reduced gain in one or more vertical channels. Lesions were found on MRI of the skull in central areas that process vestibular information, such as the cerebellum and brainstem. The association of these findings suggests the presence of central vestibular dysfunction, compatible with the lesions detected in imaging exams.
Keyphrases
- multiple sclerosis
- magnetic resonance imaging
- oxidative stress
- hearing loss
- mass spectrometry
- white matter
- healthcare
- computed tomography
- newly diagnosed
- ms ms
- contrast enhanced
- magnetic resonance
- machine learning
- prognostic factors
- health information
- diffusion weighted imaging
- drug induced
- depressive symptoms
- sleep quality
- brain injury
- fluorescence imaging