Long-Term Survival, Morbidity, Social Functioning and Risk of Disability in Patients with a Herpes Simplex Virus Type 1 or Type 2 Central Nervous System Infection, Denmark, 2000-2016.
Ann-Brit Eg HansenHanne T VestergaardRam Benny DessauJacob BodilsenNanna Skaarup AndersenLars Haukali OmlandClaus B ChristiansenSvend Ellermann-EriksenLene NielsenThomas Lars BenfieldHenrik Toft SorensenChristian Ø AndersenAnne-Mette LebechNiels ObelPublished in: Clinical epidemiology (2020)
HSV-1 and HSV-2 CNS infections differ substantially with respect to prognosis. HSV-1 CNS infection is followed by increased short-term mortality and long-term risk of disability. HSV-2 CNS infection has no substantial impact on mortality or working capability but is associated with increased morbidity.