Heme oxygenase-1 as an important predictor of the severity of COVID-19.
Yu HaraJun TsukijiAya YabeYoshika OnishiHaruka HiroseMasaki YamamotoMakoto KudoTakeshi KanekoToshiaki EbinaPublished in: PloS one (2022)
Clinically, serum HO-1, reflecting the activation of M2, could be a very useful marker for evaluating disease severity and predicting prognoses for COVID-19 patients. In addition, controlling activated M2 might be a preventative COVID-19 therapeutic target.