Carbon Black-Carbon Nanotube Co-Doped Polyimide Sensors for Simultaneous Determination of Ascorbic Acid, Uric Acid, and Dopamine.
Yue WangTian YangYasushi HasebeZhiqiang ZhangDongping TaoPublished in: Materials (Basel, Switzerland) (2018)
Carbon black (CB) and carbon nanotube (CNT) co-doped polyimide (PI) modified glassy carbon electrode (CB-CNT/PI/GCE) was first prepared for the simultaneous determination of ascorbic acid (AA), dopamine (DA), and uric acid (UA). The CB-CNT/PI/GCE exhibited persistent electrochemical behavior and excellent catalytic activities. Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) were used for the simultaneous detection of AA, DA, and UA in their ternary mixture. The peak separations between AA and DA, and DA and UA, are up to 166 mV and 148 mV, respectively. The CB-CNT/PI/GCE exhibited high sensitivity to DA and UA, with the detection limit of 1.9 µM and 3 µM, respectively. In addition, the CB-CNT/PI/GCE showed sufficient selectivity and long-term stability, and was applicable to detect AA, DA, and UA in human urine sample.
Keyphrases
- uric acid
- simultaneous determination
- carbon nanotubes
- metabolic syndrome
- liquid chromatography tandem mass spectrometry
- tandem mass spectrometry
- high performance liquid chromatography
- ultra high performance liquid chromatography
- liquid chromatography
- solid phase extraction
- label free
- endothelial cells
- loop mediated isothermal amplification
- blood pressure
- mass spectrometry
- highly efficient
- real time pcr
- high resolution
- molecularly imprinted
- capillary electrophoresis
- gas chromatography